Geno-Protective, Free Radical Scavenging and Antimicrobial Potential of Hyptis suaveolens Methanolic Fraction: An In-Vitro Study

Aims: Hyptis suaveolens (L.) Poit, is one of the natural herbs with several medicinal properties. However, many aspects this herb still need to be explored. Therefore, our aim was examine antioxidant, antimicrobial properties and genoprotective effect H. methanolic extracts (HSME) seed, stem, root.
 Study design: extraction therapeutic suaveolens.
 Place Duration Study: 1) Department Medical Laboratory Sciences, College Applied Majmaah University, Al-Majmaah 2) Clinical Biochemistry & Natural Product research laboratory, Biosciences, Integral lucknow between 2018-2020.
 Methodology: HSME were extracted through soxhlet extractor further analyzed for TPC, antioxidant activity DPPH FRAP assay followed by potential zone inhibition MIC/MBC assay. We also examined on oxidative DNA damage.
 Results: Our results showed that TPC (180±5 mg GAE/g dw), scavenging (IC50 value = 72±0.45 µg/ml) (1.443±0.02 µM ferrous ion/mg extract) highest in seeds root stem. The illustrated (seed stem) against five bacterial strain found very effective than part. Moreover, (80±3 % retention) better stem (41±2 %) (32±2 extract.
 Conclusion: study revealed seed extract bioactivities might due presence high can used treat diseases related stress or microbial infections.